The suspects identified as Patricia Wanza and Asmelder Wambui were apprehended in the operation which ended in the wee hours of Wednesday morning.
NACADA in conjunction with officers from the Directorate of Criminal Investigations, and Kenya Police also seized other contraband goods at the premises.
They include 50 alfakher flavours (gums with mint flavour), 170 pieces of flavour al-sultan, 400 coconut charcoal pieces and 16 charcoal carriers.
Others are 140 orange mint alfakher flavours, 29 blueberry mint flavours, 50 grape mint flavours and other items used in consuming shisha.
The suspects will remain in police custody at Kasarani Police Station awaiting further action.
NACADA has since December 2023 intensified its crackdown on curbing the sale and consumption of shisha products.
Over 60 raids have been conducted in clubs and party joints located in Nairobi and Mombasa.
By Moses Kinyanjui